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GH Fragment Peptide

AOD-9604 Research Peptide

AOD-9604 is a synthetic peptide fragment corresponding to residues 176-191 of human growth hormone (hGH), modified with an N-terminal tyrosine residue. It is supplied as a lyophilized powder for laboratory research applications.

Compound identity

Name
AOD-9604
Class
GH Fragment Peptide
CAS number
221231-10-3
Molecular formula
C78H125N23O23S2
Also known as
AOD9604, hGH Fragment 176-191, Anti-Obesity Drug 9604
Sequence
Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe

Research context

AOD-9604 (CAS 221231-10-3) is a 16-amino-acid peptide fragment derived from the C-terminal domain of human growth hormone. The compound consists of hGH residues 176-191 with a tyrosine appended at the N-terminus, and contains an internal disulfide bond (Cys-Cys). As a research reagent it is studied for its distinct pharmacological profile relative to full-length hGH in adipocyte cell systems.

The scientific literature on the hGH C-terminal fragment has examined its behavior in in-vitro cell assays and preclinical animal models in the context of adipose tissue biology and lipid metabolism research. AOD-9604 does not contain the N-terminal domain of hGH associated with IGF-1 stimulation, giving it a distinct binding profile that has been characterized in laboratory settings. It is not approved for human therapeutic use by the FDA or any regulatory agency.

DMV Research supplies AOD-9604 with a per-batch third-party Certificate of Analysis confirming identity and purity for research use.

Frequently asked questions

What is AOD-9604?+

AOD-9604 is a synthetic peptide fragment consisting of the C-terminal 16 amino acids of human growth hormone (hGH residues 176-191) with an N-terminal tyrosine modification. CAS 221231-10-3. It is used as a research reference compound in adipocyte and metabolic biology research.

How does AOD-9604 relate to human growth hormone?+

AOD-9604 is derived from the C-terminal domain of hGH (positions 176-191 plus a Tyr). It does not include the N-terminal domain responsible for hGH anabolic signaling and IGF-1 release, making it a structurally distinct research compound with a different receptor-binding profile.

Is AOD-9604 approved for human use?+

No. AOD-9604 is not approved for human use by any regulatory agency. As supplied by DMV Research it is for laboratory and research purposes only.

What purity is the AOD-9604 research peptide?+

Each batch is independently tested to 99%+ purity by third-party laboratories, with a Certificate of Analysis available per batch.

Research use only

All products are intended for laboratory and research use only (RUO) and are not for human consumption, ingestion, or any in-vivo use.

The statements on this page have not been evaluated by the FDA. AOD-9604 is not intended to diagnose, treat, cure, or prevent any disease. Content is provided for laboratory research reference only.